The effect of hypotermia on potassium concentration in blood cardioplegia during cardiopulmonary bypass surgery

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dc.contributor.authorPeker, Murat
dc.contributor.authorKarabayirli, Safinaz
dc.contributor.authorÖzanbarci, Azra
dc.contributor.authorÇolak, Necmettin
dc.contributor.authorDemircioğlu, Rüveyda İrem
dc.contributor.authorMuslu, Bünyamin
dc.date.accessioned2025-10-24T18:06:46Z
dc.date.available2025-10-24T18:06:46Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: Cardioplegia is quite important for myocardial protection during cardiopulmonary by-pass In order to benefit from cardioprotective effect of hypotermia cold- blood cardioplegia is commonly used. Hypotermia can alter potassium concentration. In this study we have investigated the effect of hypotermia on potassium concentration in blood cardioplegia. Material and Methods: We studied 70 patients who will undergo coronary artery bypass grafting with the aid of cardiopulmonary bypass. Potassium levels were measured from arterial blood samples of the patients before the cardiopulmonary bypass (CBP) operation. During CBP surgery, in order to achieve 16 mEq/L potassium levels, potassium was added to a 400 ml blood sample taken from cardiopulmonary pump to prepare blood cardioplegia. After addition of potassium, blood samples were deri altiwn to measure blood gases, potassium, sodium, calcium and lactate levels Blood cardioplegic solution was cooled at 4°C in an ice water container and measurements were repeated. Results: Potassium levels were detected as 16.8±0.7 mEq/L at 32°C and 16.3±0.7 mEq/L at 4°C in samples of blood cardioplegic solution (p=0.001). There was no difference bet ween analytical results of blood gases and other electrolytes. Conclusion: A decrease in potassium levels is observed after cooling blood cardioplegic solution at 4°C. However this decrease which occurs at 0.5 mEq/L concentrations may not be so important clinically. Whereas, during preparation of cardioplegic solution, estimated potassium levels were near the lower limits,m then cooling process might drop potassium levels below this lower limit. Therefore it may be helpful to keep the potassium level slightly above the target level. © 2014 Elsevier B.V., All rights reserved.
dc.identifier.doi10.5222/GKDAD.2014.016
dc.identifier.endpage20
dc.identifier.issn1305-5550
dc.identifier.issue1
dc.identifier.scopus2-s2.0-84899092811
dc.identifier.scopusqualityN/A
dc.identifier.startpage16
dc.identifier.urihttps://doi.rog/10.5222/GKDAD.2014.016
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3200
dc.identifier.volume20
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherTurkish Anaesthesiology and Intensive Care Society tsisa@logos.com.tr
dc.relation.ispartofGogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzScopus_20251023
dc.subjectCardioplegia
dc.subjectHypotermia
dc.subjectPotassium
dc.titleThe effect of hypotermia on potassium concentration in blood cardioplegia during cardiopulmonary bypass surgery
dc.title.alternativeKoroner arter baypas cerrahisinde so?uk kan kardiyoplejisi potasyum konsantrasyonu üzerine hipoterminin etkisi
dc.typeArticle

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