Dempster-Schafer Method in Family Based Association Studies

dc.contributor.authorRajabli, Farid
dc.contributor.authorGoktas, Unal
dc.contributor.authorInan, Gul
dc.date.accessioned2025-10-24T18:10:29Z
dc.date.available2025-10-24T18:10:29Z
dc.date.issued2012
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description9th International Conference on Electronics Computer and Computation (ICECCO 2012) -- NOV 01-03, 2012 -- Ankara, TURKEY
dc.description.abstractIn experiments designed for family-based association studies, methods such as transmission disequilibrium test (TDT) require large number of trios to identify single nucleotide polymorphisms (SNPs) associated with the disease. However, unavailability of large number of trios is the Achilles' heel of many complex disease studies, especially for the late-onset diseases since parents might have passed away or unavailable. This problem motivated us to look for new approaches that require smaller number of trios to detect associations in family based studies. Aiming this, we propose using Dempster-Shafer method of evidence to detect the associations in family-based studies and show that this approach has a good performance in identifying associations with moderate to small sized samples.
dc.description.sponsorshipInt Assoc Univ,Surat Technol,Yildirim Elect,BMD Solar
dc.identifier.endpage14
dc.identifier.isbn978-605-87394-6-8
dc.identifier.issn#DEĞER!
dc.identifier.startpage13
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4205
dc.identifier.wosWOS:000396806300004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherTurgut Ozal Univ
dc.relation.ispartofIcecco'12: 9th International Conference On Electronics, Computer And Computation
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectAlgorithm; genetics; Dempster-Shafer; transmission disequilibrium test; single nucleotide polymorphisms
dc.titleDempster-Schafer Method in Family Based Association Studies
dc.typeConference Object

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