Comparison of biochemical, antimicrobial and cytotoxic activities of different propolis samples from Malatya and Bilecik

Basit Öğe Kaydı
dc.authorid0000-0002-5997-2061en_US
dc.contributor.authorKeskin, Merve
dc.contributor.authorKarlıdağ, Semiramis
dc.contributor.authorYılmaz, Özgür
dc.contributor.authorTatlıcı, Eray
dc.contributor.authorKarabulut, Ercan
dc.contributor.authorApohan, Elif
dc.contributor.authorYeşilada, Özfer
dc.date.accessioned2021-06-14T06:58:01Z
dc.date.available2021-06-14T06:58:01Z
dc.date.issued2020en_US
dc.departmentMTÖ Üniversitesi, Akçadağ Meslek Yüksekokulu, Bitkisel ve Hayvansal Üretim Bölümüen_US
dc.description.abstractPropolis is a resinous natural mixtures collected and produced by honey bees. It is rich in essential oils and phenolic components so it has high levels of antioxidant, antimicrobial, anti-inflammatory and anti-tumoral activity. In this study the biochemical activity of propolis extracts were determined. The antimicrobial activity and cytotoxic activity of the extracts of the nine different propolis samples were invastigated. Their antimicrobial activities were tested by microdillution metod and define as minimum inhibitory concentration (MIC). Chemical composition of extracts was determined by using GC-MS equipment. Total phenolic content and antioxidant activity of the extracts was measured. Antimicrobial and cytotoxic activity of the extracts was carried out as well. All of the extracts showed antimicrobial activity on bacteria and yeasts used. Extracts had generally lower MIC values on yeasts. Therefore, yeasts were detected as more susceptible against the propolis extracts than the bacteria. Cytotoxic activity of extract were determined aganist A549 and Beas2B cell lines and IC50 values were calculated. Ma-Arapgir had the highest cytotoxic activity on A549 and Beas2B. They were determined as 6.72 and 26.44 mg/mL, respectively. It could be concluded that propolis extracts have antimicrobial and cytotoxic activity thus, propolis could be used in the treatment of cancer. © 2020 SYSCOM 18 S.R.L.. All rights reserved.en_US
dc.identifier.citationKeskin, M., Karlıdağ, S., Apohan, E., Yılmaz, O., Tatlıcı, E., Apohan, E., Yesilada, O., ... Karabulut, E. (January 01, 2020). Comparison of biochemical, antimicrobial and cytotoxic activities of different propolis samples from Malatya and Bilecik. Revista De Chimie, 71, 5, 355-362.en_US
dc.identifier.doi10.37358/RC.20.5.8144
dc.identifier.endpage362en_US
dc.identifier.issn2668-8212en_US
dc.identifier.issn0034-7752en_US
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85086369018en_US
dc.identifier.startpage355en_US
dc.identifier.urihttps://doi.org/10.37358/RC.20.5.8144
dc.identifier.urihttps://hdl.handle.net/20.500.12899/243
dc.identifier.volume71en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKarlıdağ, Semiramis
dc.language.isoenen_US
dc.publisherRevista de Chimie SRLen_US
dc.relation.ispartofRevista de Chimieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPropolisen_US
dc.subjectA549en_US
dc.subjectBeas2Ben_US
dc.subjectAntimicrobial activityen_US
dc.subjectCytotoxic activityen_US
dc.titleComparison of biochemical, antimicrobial and cytotoxic activities of different propolis samples from Malatya and Bileciken_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Merve Keskin-Makale Dosyası.pdf
Boyut:
624.05 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu