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    Causes of COVID-19’s Mortality and Prognostic Effect of Neutrophile-Lymphocyte Ratio
    (2022) Öterkuş, Mesut; Acun Delen, Leman
    Objectives: In this study, we aimed to investigate the prognostic value of the neutrophile-lymphocyte ratio and the effects of age, gender, and comorbidities on mortality. Methods: In our study, 100 patients who had a ground-glass opacification on computed thorax tomography and who had a positive polymerase chain reaction test were included in our study. Demographic data, laboratory data and comorbidities of the patients were recorded. Results: Sixty-five (65%) of the patients participating in the study were male. The mean age of the patients was 66 (21.5). The mortality rate was found to be 27% (n=27) High neutrophile-lymphocyte ratio, low lymphocyte count, high urea, and creatin levels were significant in terms of mortality. In addition, advanced age, diabetes mellitus, and hypertension are other factors that have an impact on mortality. Conclusion: The neutrophile-lymphocyte ratio can solely be used as a prognostic marker because it is simple and economical.
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    An evaluation of cost analysis of palliative care centers
    (Oterkus, Mesut, 2022) Dişli, Zeliha Korkmaz; Acun Delen, Leman; Erce, Çiğdem; Ötekuş, Mesut
    Palliative care services were established in order to reduce the work and patient burden of intensive care units (ICU) and to reduce the treatment and care costs of patients. We objectives to make a reference study for the determination and planning of expenditure items by making expense analyzes of these centers. The files of 149 patients hospitalized in the palliative care center of Malatya Training and Research Hospital were reviewed retrospectively. The hospital automation system and files were analyzed and recorded for the data of the patients. Demographic data of patients, diagnoses of hospitalization, length of stay, treatment and care costs, including, antibiotics and other drugs, nutrition, wound care, laboratory and imaging studies, consultations, and daily bed costs were recorded and evaluated. 72 (48%) of the patients were male and the mean age was 75.4±13.0 years. The most common indications for hospitalization were malignancy 35.6% (n:53) and cerebrovascular disease (CVD) 33.6% (n:50). The average cost per patient was 7700 Turkish Liras (TL). It was found that the most important expenditure items in the palliative care center were daily cost of bed (6835 TL) per day), non-antibiotic drugs (2395 TL), and nutrition (1087 TL), respectively. Palliative care services are very effective units in reducing the care and treatment expenses of hospitals, which reduces the work and patient burden of intensive care units. In this respect determining and analyzing the costs of expenditure items will play an important role in health planning.
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    Sinovac vaccination and the course of COVID-19 disease in hospitalized patients in Turkey
    (King Faisal Specialist Hospital and Research Centre, 2022) Acun Delen, Leman; Öterkuş, Mesut
    BACKGROUND: The Alpha variant of SARS-CoV-2 has a higher transmission rate than the first variant identified. The efficacy of vaccines is affected by the characteristics of SARS-CoV-2 variants. OBJECTIVE: Investigate the relationship of vaccination and virus variant on the course of the disease in patients who were hospitalized with a diagnosis of COVID-19. DESIGN: Retrospective, cohort study SETTING: Tertiary health institution PATIENTS AND METHODS: The study included patients older than the age of 18 years who were hospitalized in a COVID-19 service or the intensive care unit with a diagnosis of COVID-19 between 1 January 2021 and 30 April 2021. Demographic characteristics, vaccination and the Alpha virus variant status, comorbidities, and information about hospitalization were obtained from the hospital automation system and patient files. MAIN OUTCOME MEASURES: Vaccination rate and relationship with course of disease. SAMPLE SIZE: 608 RESULTS: Most of the patients (n=482, 79.3%) were admitted to the COVID-19 service. More of the COVID-19 service patients had the Alpha variant than the patients admitted to ICU (P<.009). The Alpha variant was also more common in younger patients (P<.001). There was no relationship between the Alpha virus and comorbid diseases such as diabetes mellitus and hypertension. Mortality was lower in the patients who had received a second dose of the Sinovac vaccine (P=.004) compared with unvaccinated patients. CONCLUSION: Although the Alpha variant spreads faster, it has a milder course. If only the Sinovac vaccine is available, we recommend that the two doses of the Sinovac vaccine be administered. LIMITATIONS: Our study is single-center and did not include pregnant and pediatric patients. CONFLICT OF INTEREST: None.