Duran, MuzeyyenUstunyurt, EminKosus, AydinKosus, NerminTurhan, NilgunHizli, DenizSarac, Gulce Naz2025-10-242025-10-2420140301-21151872-7654https://doi.org/10.1016/j.ejogrb.2014.01.020https://hdl.handle.net/20.500.12899/3416Objective: To assess the histomorphological effects of smoking on the cilia of fallopian tubes in mice and the effect of vitamin E on the negative effects of smoke. Study design: Eighteen 12-14 week-old Swiss albino type female mice were randomly divided into three groups, each consisting of six mice: Group A: control group; Group B: mice exposed to cigarette smoke; Group C: mice exposed to cigarette smoke together with vitamin E. Groups B and C were exposed to cigarette smoke for 10 weeks. After 10 weeks, tubal excision was performed in all animals. Histopathologic examination of excised tubal tissue was conducted under light microscopy. Results: The number of cilia was significantly lower in Group B. Although not statistically significant, the median number of cilia in Group C was measured to be higher than in Group B but lower than in Group A. Conclusion: Based on the results, it can be concluded that smoking decreases tubal cilia numbers. Supplementation by vitamin E may treat or at least help to slow down the decrease in number of cilia caused by smoking; therefore it could be used therapeutically in the treatment of smoking-related tubal damage. Crown Copyright (C) 2014 Published by Elsevier Ireland Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessSmoking; Fallopian tubes; Infertility; Cilia number; Vitamin EArticle10.1016/j.ejogrb.2014.01.020175149151245301902-s2.0-84898058077Q2WOS:000335432000027Q3