Guler, EmreTotan, YukselHepsen, Ibrahim F.Tenlik, Aylin2025-10-242025-10-2420181542-23211542-233Xhttps://doi.org/10.1097/ICL.0000000000000003https://hdl.handle.net/20.500.12899/3566Objective: To report a case of unilateral spontaneous descemet membrane rupture associated with megalophthalmos. Methods: A case report of a 23-year-old woman with blurred vision of the right eye for 6 months due to spontaneous descemet membrane rupture associated with megalophthalmos is described. Slit-lamp examination demonstrated corneal edema and suggestion of a descemet membrane rupture in the right eye. Results: Anterior segment optical coherence tomography verified the presence of a ruptured descemet membrane separated from the nasal posterior cornea along with corneal edema and intraepithelial cystic lesions. With A-scan ultrasonography, axial lengths were 32 and 28 mm in OD and OS, respectively. Indirect gonioscopy demonstrated a wide iridocorneal angle and a ciliary body band, bilaterally. Corneal pachymetry measurements were performed with Pentacam HR Scheimpflug topography which measured the central corneal thickness 360 mu in OD and 300 mu in OS. Conclusions: Megalophthalmos and spontaneous descemet membrane rupture are rare conditions. To the best literature knowledge, this is the first report of descemet membrane rupture in megalophthalmos.eninfo:eu-repo/semantics/closedAccessDescemet membrane; Megalophthalmos; Spontaneous ruptureArticle10.1097/ICL.0000000000000003441E4E6269255342-s2.0-84959278742Q1WOS:000441175300002Q2