Özgür, Mustafa Erkan2021-06-102021-06-102019Özgür, M. E. (October 01, 2019). The protective effects of Vitamin C and Trolox on kinematic and oxidative stress indices in rainbow trout sperm cells against flower‐like ZnO nanoparticles. Aquaculture Research, 50, 10, 2838-2845.1355-557Xhttps://doi.org/10.1111/are.142361365-2109https://hdl.handle.net/20.500.12899/214This study investigated the protective effects of 1 mM Vitamin C and 1 mM Trolox on kinematic and oxidative stresses in rainbow trout (Oncorhynchus mykiss) sperm cells against flower-like zinc oxide nanoparticles (ZnO-NP, 1 mg/L) in vitro, during 2 hr. Trolox showed protective effects on all kinematic parameters measured for sperm cells against ZnO-NPs, whereas Vitamin C only affected angular path velocity (VAP), linearity (LIN) and amplitude of lateral displacement of the sperm cell head (ALH). Although ZnO-NPs reduced total glutathione (TGSH) and catalase (CAT) compared with the control, there were positive treatment effects for both Trolox and Vitamin C on antioxidant capacity. Conversely, while ZnO-NP increased the rate of malondialdehyde (MDA) lipid peroxidation, it decreased following antioxidant therapy. This research suggests that Trolox and Vitamin C play a protective role for rainbow trout sperm exposed to ZnO-NP.eninfo:eu-repo/semantics/closedAccessAntioxidantsOxidative stress indicesRainbow troutSperm cells kinematicsZnO nanoparticlesArticle10.1111/are.142365010283828452-s2.0-85068234928Q2WOS:000473758100001Q2