Peker, MuratKarabayirli, SafinazÖzanbarci, AzraÇolak, NecmettinDemircioğlu, Rüveyda İremMuslu, Bünyamin2025-10-242025-10-2420141305-5550https://doi.rog/10.5222/GKDAD.2014.016https://hdl.handle.net/20.500.12899/3200Objective: Cardioplegia is quite important for myocardial protection during cardiopulmonary by-pass In order to benefit from cardioprotective effect of hypotermia cold- blood cardioplegia is commonly used. Hypotermia can alter potassium concentration. In this study we have investigated the effect of hypotermia on potassium concentration in blood cardioplegia. Material and Methods: We studied 70 patients who will undergo coronary artery bypass grafting with the aid of cardiopulmonary bypass. Potassium levels were measured from arterial blood samples of the patients before the cardiopulmonary bypass (CBP) operation. During CBP surgery, in order to achieve 16 mEq/L potassium levels, potassium was added to a 400 ml blood sample taken from cardiopulmonary pump to prepare blood cardioplegia. After addition of potassium, blood samples were deri altiwn to measure blood gases, potassium, sodium, calcium and lactate levels Blood cardioplegic solution was cooled at 4°C in an ice water container and measurements were repeated. Results: Potassium levels were detected as 16.8±0.7 mEq/L at 32°C and 16.3±0.7 mEq/L at 4°C in samples of blood cardioplegic solution (p=0.001). There was no difference bet ween analytical results of blood gases and other electrolytes. Conclusion: A decrease in potassium levels is observed after cooling blood cardioplegic solution at 4°C. However this decrease which occurs at 0.5 mEq/L concentrations may not be so important clinically. Whereas, during preparation of cardioplegic solution, estimated potassium levels were near the lower limits,m then cooling process might drop potassium levels below this lower limit. Therefore it may be helpful to keep the potassium level slightly above the target level. © 2014 Elsevier B.V., All rights reserved.trinfo:eu-repo/semantics/openAccessCardioplegiaHypotermiaPotassiumArticle10.5222/GKDAD.2014.01620116202-s2.0-84899092811N/A