Özgür, Mustafa ErkanUlu, AhmetÖzcan, İmrenBalcıoğlu, SevgiAteş, BurhanKöytepe, Süleyman2021-08-262021-08-262019Özgür, M. E., Ulu, A., Özcan, İ., Balcioglu, S., Ateş, B., & Köytepe, S. (2019). Investigation of toxic effects of amorphous SiO 2 nanoparticles on motility and oxidative stress markers in rainbow trout sperm cells. Environmental Science and Pollution Research, 26, 15641-15652.0944-13441614-7499https://doi.org/10.1007/s11356-019-04941-5https://hdl.handle.net/20.500.12899/368In this study, we investigated the effects of SiO2 nanoparticles (SiO2-NPs) (1, 10, 25, 50, and 100 mg/L) for 24 h in vitro on the motility parameters and oxidative stress markers such as total glutathione (TGSH), catalase (CAT), and malondialdehyde (MDA) of rainbow trout, Oncorhynchus mykiss sperm cells. Therefore, SiO2-NPs were synthesized with sol-gel reaction from tetraethoxy orthosilicate (TEOS). The prepared nanoparticle structures were characterized for chemical structure, morphology and thermal behavior employing Fourier transform infrared spectroscopy, X-ray spectroscopy, scanning electron micrograph, and thermal analysis (DTA/TGA/DSC) techniques. After exposure, there was statistically significant (p <?0.05) decreases in velocities of sperm cells. CAT activity significantly (p?< 0.05) decreased by 9.6% in sperm cell treated with 100 mg/L. In addition, MDA level significantly increased by 70.4% and 77.5% in sperm cell treated with 50 and 100 mg/L SiO2-NPs, respectively (p?< 0.05). These results showed that SiO2-NPs may have toxic effect on rainbow trout sperm cells in 50 mg/L and more.eninfo:eu-repo/semantics/closedAccessSiO2-NPsRainbow troutSperm cell motilityCASA analysisCATMDAArticle10.1007/s11356-019-04941-5261564115652309499422-s2.0-85066147890Q1WOS:000468842100082Q2