AKTAR, BEDRİYE SEDA KURSUNSICAK, Yusuforuç-emre, emine elçin2025-10-242025-10-2420222602-277Xhttps://doi.org/10.32571/ijct.1003871https://search.trdizin.gov.tr/tr/yayin/detay/1104559https://hdl.handle.net/20.500.12899/2472A series of E-4-(3-oxo-3-(substituted)prop-1-en-1-yl)benzoic acid derivatives (1-5) were synthesized by the Claisen-Schmidt condensation of various ketones with 4-formylbenzoic acid. The anticholinesterase (AChE and BChE), tyrosinase, and urease inhibition activities of the synthesized compounds (1-5) were examined. It was found that the most active compound against AChE enzyme in anticholinesterase inhibition activity was compound 1. Compound 4 was the most active compound in tyrosinase inhibition activity, while compound 3 was the most active compound in urease psychological activity.eninfo:eu-repo/semantics/openAccessKimyaOrganikBiyokimya ve Moleküler BiyolojiChalconeUrease inhibitory activityAnticholinesterase activityTyrosinase inhibitory activityArticle10.32571/ijct.1003871617141104559