Öztan, ÖzgürTürksoy, Vugar AliDeniz, Serdarİritaş, Servet BirginTutkun, Engin2022-03-162022-03-162021-07-11OZTAN, O., Türksoy, V. A., Deniz, S., İRİTAŞ, S. B., & TUTKUN, E. The association between PTX3 and serum manganese levels of welders in comparison with controls: An application of anti-inflammatory biomarker. Journal of Health Sciences and Medicine, 4(4), 511-515.https://dergipark.org.tr/tr/download/article-file/184473810.32322/jhsm.957953https://hdl.handle.net/20.500.12899/671Aim: The purpose of this study was to compare serum PTX3 levels of manganese-exposed welders with non-exposed controls to evaluate the nature of the manganese-induced inflammatory response. Material and Method: Overall, we collected 103 research samples (Mn-Exposed Welders Group:51 and Non-Exposed Controls: 52). PTX-3 levels were analyzed in the serum samples by the ELISA method, while Mn levels in whole blood specimens were quantified by the inductively coupled plasma (ICP-MS) method. Results: The mean values of manganese and Pentraxin-3 of the control group were found to be significantly lower than those of the exposure group (Mn levels: 5.04±2.32 µg/L vs. 11.54±3.09 µg/L; PTX-3: 36.96±24.20 ng/mL vs. 48.29±27.13 ng/mL; p<0.05). Conclusion: This hypothetical and observational investigation highlighted the relationship between Mn levels and PTX-3 for the first timeeninfo:eu-repo/semantics/openAccessManganeseExposurePentraxin-3İnflammationArticle10.32322/jhsm.95795344511515