Akyol, SumeyyaUgurcu, VeliBalci, MehmetGurel, AyseErden, GonulCakmak, OzlemAkyol, Omer2025-10-242025-10-2420141080-76831557-7732https://doi.org/10.1089/jop.2014.0046https://hdl.handle.net/20.500.12899/3557As an effective compound found mainly in the honeybee product propolis, caffeic acid phenethyl ester (CAPE) has been commonly utilized as a medicine and remedial agent, in a number of countries. Specifically, it might inhibit nuclear factor kappa B at micromolar concentrations and demonstrate antioxidant, antineoplastic, antiproliferative, cytostatic, antiviral, antibacterial, antifungal, and anti-inflammatory features. This review article summarizes the recent progress regarding the favorable effects of CAPE on a number of eye disease models, including cataract and posterior capsule opacification, corneal diseases, retina and optic nerve-related diseases, ischemia/reperfusion injury of retina, inflammation and infection-related diseases. CAPE has been found to exhibit promising efficacy, with minimal adverse effects, in animal and cell culture studies of several eye diseases.eninfo:eu-repo/semantics/closedAccessStaphylococcus-Epidermidis Endophthalmitis; Endotoxin-Induced Uveitis; Endothelial Growth-Factor; Pigment Epithelial-Cells; Induced Diabetic-Rats; Ischemia-Reperfusion; Oxidative Stress; Mouse Skin; Proliferative Vitreoretinopathy; Ischemia/Reperfusion InjuryReview Article10.1089/jop.2014.0046309700708251005352-s2.0-84932120375Q1WOS:000344386300004Q3