Onaran, YukselKafali, HasanDuvan, Candan IltemirKeskin, EsraCelik, HakimErel, Ozcan2025-10-242025-10-2420141476-70581476-4954https://doi.org/10.3109/14767058.2013.842549https://hdl.handle.net/20.500.12899/3801Objective: To evaluate oxidant and antioxidant activity in patients with hyperemesis gravidarum (HG) by using serum total antioxidant activity (TAO), total free sulfhydryl (-SH), ceruloplasmin and lipid hydroperoxide (LOOH) levels. Materials and methods: In a cross-sectional trial, blood samples were collected from patients with HG (n = 25) and healthy pregnant women (n = 25) as control group. Serum TAO activities, -SH levels and LOOH levels and ceruloplasmin levels were measured. Results: Serum TAO activity was found to be significantly lower (p = 0.003) in patients with HG compared with controls. However, serum -SH levels, LOOH levels and ceruloplasmin levels did not change significantly in patients with HG compared to controls. Conclusion: Presence of oxidative stress in HG patients depends more on reduced antioxidant activities than increased oxidative stress.eninfo:eu-repo/semantics/closedAccessAntioxidant activity; hyperemesis gravidarum; pregnancyArticle10.3109/14767058.2013.842549278825828240410312-s2.0-84898912500Q1WOS:000334738800011Q3