Yagar, HilalVural, AbdussamedDolanbay, Turgut2026-06-192026-06-1920252458-89382564-7288https://doi.org/10.30621/jbachs.1451540https://hdl.handle.net/20.500.12899/5325Purpose: Diabetic foot ulcers are one of the important reasons for amputations. The hemoglobin-albumin-lymphocyte-platelet (HALP) score is a marker of the inflammatory and nutritional status of the individual. Aim of this study is to investigate the relationship between the HALP score and mortality in patients undergoing above-ankle amputation due to diabetic foot infection. Material and Methods: The demographic data (age, sex), deaths during hospitalization, laboratory values and mortality through 3-6-9-12 months were recorded. Chi square and t test were used for categorical comparison and logistic regression tests were used for mortality risk estimation. Results: The mortality rates in hospital and in the 3rd, 6th, 9th, and 12th months were 13.1%, 37.7%, 48.5%, 53.8%, and 56.2% respectively. HALP score below 21.55 was associated with a 2.975 times higher risk for 1-year mortality (odds ratio: 2.975; 95% CI: 1.252-7.069; p = 0.014). Female gender, HALP score below 21.55, and age over 65 predict 20.2% overall 1-year mortality risk (Nagelkerke R2 = 0.202). Conclusion: The HALP score is a novel risk factor for mortality in patients undergoing amputation for diabetic foot ulcers. Also; older age and female gender are independent risk factors for 1-year mortality.eninfo:eu-repo/semantics/openAccessDiabetic FootRisk Factor ScoresPrognosisAmputationMortalityArticle10.30621/jbachs.145154092WOS:001510788800002Q40000-0003-4506-916X0000-0001-5544-0458