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  • Küçük Resim Yok
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    Evaluation of arterial stiffness in patients with generalized anxiety disorder
    (2023) Yildiz, Sevler; Kılıçaslan, Aslı Kazğan; Uğur, Kerim; kurt, osman; KILIÇARSLAN, GÜLHAN
    Purpose: Generalized anxiety disorder (GAD) is a psychiatric condition where both physical and mental symptoms are observed due to the activation of the sympathetic system. It is known that the disorder affects the cardiovascular system. The present study aimed to analyze arterial stiffness in GAD patients and compare the findings with healthy controls. Materials and Methods: 40 patients diagnosed with GAD and 40 healthy individuals were included in the study. Carotid and femoral artery intima-medial thickness (IMT) and arterial thickness parameters were measured with Doppler ultrasonography. Results: The femoral IMT of the patients was significantly low. Although the carotid IMT was higher in patients when compared to the controls, the difference was not statistically significant. A significant negative correlation was determined between fluoxetine equivalent dose and femoral IMT. There was a correlation between femoral IMT and fluoxetine equivalent dose. Conclusion: Arterial stiffness should be investigated for its potential to indicate cardiovascular risk in GAD. Further comprehensive studies should be conducted to clarify whether atherosclerosis symptoms were associated with the nature of the GAD or prescription medicine.
  • Küçük Resim Yok
    Öğe
    Markers of inflammation in patients with generalized anxiety disorder
    (2024) Yildiz, Sevler; Kılıçaslan, Aslı Kazğan; Emir, Burcu Sırlıer; TABARA, Muhammed Fatih; kurt, osman; SEHLİKOĞLU, ŞEYMA; Uğur, Kerim
    Purpose: The aim of this study was to analyze the systemic immune response index, systemic immune inflammation index, neutrophil/HDL, lymphocyte/HDL, platelet/HDL, and monocyte/HDL ratio, used as inflammatory markers in patients with generalized anxiety disorder (GAD). Materials and Methods: A total of 864 participants, including 432 healthy controls and 432 patients diagnosed with GAD, were included in this study. High-density lipoprotein (HDL-c) levels, neutrophil, monocyte, lymphocyte, and platelet counts; systemic inflammatory response index (SIRI), systemic immune-inflammatory index (SII), neutrophil/high-density lipoprotein ratio (NHR), lymphocyte/high-density lipoprotein ratio (LHR), monocyte/high-density lipoprotein ratio (MHR), and platelet/high-density lipoprotein ratio (PHR) were calculated. Results: The median age of the case group was 35.50 (interquartile range: 28.00-44.00), while the median age of the control group was 35.00 (interquartile range: 28.00-44.00). In the GAD group, neutrophils, monocytes, SII, SIRI, NHR, LHR, MHR, and PHR were significantly higher, while platelets and HDL were significantly lower. Conclusions: This study highlights that elevated systemic inflammation markers, such as SII and SIRI, along with altered HDL ratios, may be associated with GAD. The findings support the hypothesis that inflammation plays a role in the etiopathogenesis of GAD, potentially contributing to both diagnosis and management.
  • Küçük Resim Yok
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    Methods of Coping With Psychological Pain and Stress in Antisocial Personality Disorder
    (2023) Emir, Burcu Sırlıer; Yildiz, Sevler; Kılıçaslan, Aslı Kazğan; SEHLİKOĞLU, ŞEYMA; kurt, osman; Uğur, Kerim
    Aim: Antisocial Personality Disorder (ASPD) is a personality dis - order in which the person has difficulty controlling his behaviors and impulses, harming both himself and his environment. In our study, we aimed to examine the psychological pain experienced by people with ASPD and the methods of coping with the stress they use to combat it. Material and Method: Forty patients and 40 healthy control groups were included in the study. Sociodemographic Data Form, Beck Depression Scale (BDI), Beck Suicide Scale (BSS), Psychache Scale (PS), and Styles of Coping with Stress (SCSS) were administered to the participants. Results: The BDI (p=0.037), BSS (p=0.009), PS (p=0.008) and SCSS-helpless approach (p=0.01) scores of the patients in the pa - tient group were significantly higher than the scores of the control group. On the other hand, the scores of SCSS-self-confident ap - proach (p=0.001) and SCSS-searching for social support (p<0.001) were found to be significantly lower than the scores of the control group. In the patient group, there was a positive correlation between BDI and BSS, PS and SCSS-optimistic approach. On the other hand, there was a significant negative correlation between BDI and SCSS-self-confident approach and SCSS-seeking social support Conclusion: In our study, depression, suicide, and psychological pain were found to be significantly higher in people with ASPD compared to the control group, and it was determined that they used ineffective coping strategies. We think that early interventions for the treatment of psychological pain, such as suicidal ideation, determination of depression, and providing support for using ef - fective coping strategies, may be effective in preventing self-de - structive behaviors or suicides in ASPD, and therefore may change the course of the disease.
  • Küçük Resim Yok
    Öğe
    Resilience, depression and burnout levels in caregivers of patients followed in the forensic psychiatry service
    (2023) Yildiz, Sevler; Kılıçaslan, Aslı Kazğan; Emir, Burcu Sırlıer; kurt, osman; Uğur, Kerim
    Objective: It is known that psychiatric diseases also affect the quality of life of patients' relatives. The aim of this study is to examine the level of resilience, depression and burnout of the caregivers of forensic psychiatry patients in order to recognize the mental problems that may be experienced by relatives of forensic psychiatry patients who have com- mitted crimes in addition to psychiatric illness. Method: 90 high-security forensic psychiatry patient relatives were included in the study. Sociodemographic data form, Beck Depression Inventory (BDI), Adult Resilience Scale (RSA) and Maslach Burnout Inventory (MBI) were admi- nistered to all participants. Results: BDI score of caregivers was 10.8±7.7, RSA-total 99.8±12.5, emotional burnout score from MBI subscales 22.5±3.4, depersonalization score 9.4±2.2, personal success score was determined as 16.8±5.4. There was a signifi- cant difference between the duration of caregiving in terms of BDI score (p<0.01). The BDI score of the caregivers of the patients with criminal liability was found to be significantly higher than the score of the caregivers of the patients without criminal liability (p< 0.01). Discussion: It was observed that the level of psychological resilience was good in people who took care of psychiatric patients who were subjected to forensic psychiatric examination, but they had mild depression and moderate burnout. It is seen that the relatives of the patients are affected psychologically and the necessary psychosocial support can be positive for the caregivers.
  • Küçük Resim Yok
    Öğe
    Sağlık Kuruluna Başvuran Nörolojik Tanılı Hastaların Demografik ve Klinik Verilerinin Retrospektif Değerlendirilmesi
    (2022) Tasci, Irem; Bakır, Meryem; ALGÜL, Fatma Ebru; kurt, osman
    Amaç: Engellilik oluşturan nörolojik hastalıklar, pahalı tedavi\rmaliyetleri ve belirgin iş gücü kaybına neden olabilirler. Bu çalışmada,\rOcak-Aralık 2017 tarihleri arasında hastanemizin Engelli Sağlık Kuruluna\rbaşvuran nörolojik tanılı hastaların demografik ve klinik verilerini\rdeğerlendirmeyi amaçladık. Gereç ve Yöntem: Ocak-Aralık 2017\rtarihleri arasında hastanemizin Engelli Sağlık Kuruluna engelli raporu\riçin başvuran hastalar retrospektif olarak taranmış; yaş, cinsiyet, tanısı,\rbaşvuru nedeni ve özür oranı tespiti yapılmıştır. Bulgular: Çalışmaya\r1.870 nörolojik tanısı olan hasta dâhil edilmiştir. Kadın yaş ortalaması,\rerkeklerden anlamlı derecede yüksek tespit edilmiştir (p<0,001). En sık\rbaşvurunun, bakım hizmeti için olduğu gözlenmiştir. En sık başvuru\rtanısı demans tanısı ile olup, yaş ortalaması ve engellilik oranı en fazla\rdemansta tespit edilmiştir. Hem Parkinson hastalığında hem de demansta\rerkeklerin özürlülük oranı, kadınlarınkinden daha fazla bulunmuştur;\rfakat bu fark sadece demans tanısında istatistiksel açıdan\ranlamlı bulunmuştur. En genç yaş grubu ve en az engellilik oranları, serebral\rpalsi ve epilepsi grubunda izlenmiştir. Demans hastalarının\r1/3’ünde işitme kaybı olduğu tespit edilmiştir. Serebrovasküler hastalıklara\ren sık eşlik eden hastalık %30,5 sıklıkla hipertansiyon iken; en\raz eşlik eden hastalık %0,4 sıklıkla atriyal fibrilasyon olarak tespit\redildi. Sonuç: Bu ve benzeri çalışmalar, engelliğe neden olan hastalıkları\rbelirleyerek, ilgili hastalıkların profilaksi ile önlenmesine; hastaların\rrehabilitasyon çalışmaları ile topluma kazandırılmasına yol\rgösterici olacak ve toplumsal maliyeti azaltacaktır.

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