Yazar "Yuce, Ebru" seçeneğine göre listele

Listeleniyor 1 - 5 / 5
  • Küçük Resim Yok
    Öğe
    Correlations of maternal neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) with birth weight
    (Taylor & Francis Ltd, 2017) Akgun, Nilufer; Kalem, Muberra Namli; Yuce, Ebru; Kalem, Ziya; Aktas, Hatice
    Objective: The aim of this study is to investigate the possible correlation of hemogram parameters including neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) with birth weight and gestational week.Materials and methods: This prospective study has been conducted with 783 patients. The maternal age, parity, gestational age, type of delivery, values of complete blood count (CBC) variables and the weight of newborn were recorded. We analyzed the statistical differences between the NLR, PLR, hemoglobin (HGB), platelet distribution width (PDW), red cell distribution width (RDW), mean platelet volume (MPV), platelet, neutrophil, lymphocyte and white blood cells (WBC) in terms of the birth weight.Results: There was no statistically significant difference in the NLR in terms of the birth weight (p=0.097), whereas there was a statistically significant difference in the PLR (p<0.001). In correlation analyses, a linear, negative, weak and statistically significant correlation was detected between NLR and PLR with the birth weight of infant and gestational week (p=0.011 and p<0.001, respectively).Conclusion: This prospective study is the first in the literature which investigates the correlation of NLR and PLR with the week of birth and birth weight of the infant. Our study suggested that the maternal NLR and PLR are negatively correlated with the week of birth and birth weight of the infant.
  • Küçük Resim Yok
    Öğe
    Effects of the etonogestrel contraceptive implant (Implanon®) on bone metabolism during lactation: a prospective study
    (Bmj Publishing Group, 2017) Duvan, Candan Iltemir; Onaran, Yuksel; Keskin, Esra Aktepe; Yuce, Ebru; Yanik, Burcu; Kafali, Hasan; Turhan, Nilgun Ozturk
    Aim To evaluate the effects of the etonogestrel contraceptive implant (Implanon (R)) on bone metabolism in lactating women using markers for bone formation and resorption. Study design This single-centre, prospective cohort study was conducted in Turgut Ozal University Medical Faculty Obstetrics and Gynecology Department with healthy lactating women aged between 24 and 38 years to compare the effect on bone metabolism of 6 months' use of either the implant or a non-hormonal contraceptive method. The study group (n=25) used an implant and the control group (n=25) used a non-hormonal contraceptive intrauterine device inserted 40 days' postpartum. Bone metabolism differences at the time of insertion and after 6 months were assessed quantitatively by biochemical analysis of serum and urine samples. Results At baseline, serum levels of bone metabolism parameters were similar for the two groups. In the implant group, serum alkaline phosphatase (ALP) levels decreased (p=0.004) and total protein levels increased (p=0.045) at 6 months. In the control group, serum levels of bone metabolism parameters did not change at 6 months compared to baseline. However, serum levels of phosphorus (p=0.013) and ALP (p=0.003) decreased at 6 months compared to baseline. Conclusion Six months' postpartum use of Implanon was found to have no deleterious impact on bone turnover in healthy lactating women.
  • Küçük Resim Yok
    Öğe
    Electrocardiographic P-Wave Duration, QT Interval, T Peak to End Interval and Tp-e/QT Ratio in Pregnancy with Respect to Trimesters
    (Wiley, 2016) Tanindi, Asli; Akgun, Nilufer; Pabuccu, Emre Goksan; Gursoy, Asli Yarci; Yuce, Ebru; Tore, Hasan Fehmi; Duvan, Candan Iltemir
    Background: P-wave duration helps to determine the risk of atrial arrhythmia, especially atrial fibrillation. QT interval, T peak to end interval (Tp-e), and Tp-e/QT ratio are electrocardiographic indices related to ventricular repolarization which are used to determine the risk of ventricular arrhythmias. We search for any alterations in electrocardiographic indices of arrhythmia in the pregnancy period with respect to trimesters. Methods: We enrolled 154 pregnant and 62 nonpregnant, healthy women into this cross-sectional study. Maximum and minimum P-wave durations (Pmax, Pmin), and QT intervals (QTmax, QTmin) were measured from 12 leads. QT measurements were corrected using Fridericia (QTc-Fr) and Bazett's (QTc-Bz) correction. Tp-e interval was obtained from the difference between QT interval, and QT peak interval (QTp) measured from the beginning of the QRS until the peak of the T wave. Tp-e/QT ratio was calculated using these measurements. Results: Pmax were 93.0 +/- 9.1, 93.9 +/- 8.9, 97.9 +/- 5.6, 99.0 +/- 6.1 in nonpregnant women, first, second, third trimesters of pregnancy, respectively (P = 0.001); whereas Pmin values were not significantly different. QTc-Fr max were 407.4 +/- 14.2, 408.5 +/- 16.1, 410.1 +/- 13.1, 415.1 +/- 10.1 (P = 0.007); Tp-e were 72.7 +/- 6.2, 73.2 +/- 6.5, 77.2 +/- 8.9, 87.2 +/- 9.6 (P < 0.001); and Tp-e/QT were 0.17 (0.14-0.20), 0.17 (0.14-0.20), 0.18 (0.15-0.23), 0.20 (0.16-0.25) in nonpregnant women, first, second, and third trimesters of pregnancy respectively (P < 0.001). None of the participants experienced any arrhythmic event. Conclusions: P-wave duration is prolonged in the second trimester, and resumes a plateau thereafter. Maximum QTc interval, Tp-e interval and Tp-e/QT ratio are increased in the late pregnancy. Although these indices are altered during the course of pregnancy, they all remain in the normal ranges.
  • Küçük Resim Yok
    Öğe
    Misdiagnosis of macroamylasemia in pregnancy as pancreatitis
    (Walter De Gruyter Gmbh, 2015) Eser, Ayla; Akgun, Nilufer; Yuce, Ebru; Kafali, Hasan
    Background: While elevated serum amylase in the presence of abdominal pain can be indicative of pancreatitis, differential diagnosis of macroamylasemia depends on additional assessment of serum lipase and urinary amylase. The present report concerns misdiagnosis of pancreatitis in a pregnant woman with elevated serum amylase but normal lipase. Highlights: The patient was a nulligravid woman on her first pregnancy diagnosed with pancreatitis in her 32nd week plus 3 days of gestation, on the basis of elevated serum amylase and abdominal pain, after treatment for premature contractions and antepartum vaginal bleeding with ritodrine HCl and nifedipine. She was started on painful and invasive intravenous hydration; oral intake was stopped. Repeat elevated serum amylase suggested that the patient might in fact have macroamylasemia, not pancreatitis. Conclusions: Normal serum lipase levels should be considered as a likely indication of an alternative cause of elevated serum amylase to pancreatitis, and urinary amylase should be routinely checked to assist in differential diagnosis to avoid unnecessary and invasive treatment and stress to pregnant women.
  • Küçük Resim Yok
    Öğe
    Problems of modern approaches to management of early pregnancy failure
    (Galenos Yayincilik, 2015) Kalem, Muberra Namli; Kalem, Ziya; Yuce, Ebru; Eser, Ayla; Duvan, Zehra Candan Iltemir
    In the last 20 to 30 years, early diagnosis of pregnancy has markedly decreased ectopic pregnancy-related maternal mortality, and the necessity for surgical treatment. With modern approaches in the treatment of ectopic pregnancy, surgical therapy has been replaced by medical therapy and medical treatment by spontaneous follow-up in appropriate cases. However, this current trend has led to some problems, including the maximization of ultrasonographic interpretations, misunderstandings in serial human koryonik gonadotropin hormon measurements, and complications due to inappropriate methotrexate use. The aim of the present study was to review the literature relating to the diagnosis and follow-up of early pregnancies, to underline some of the important considerations, and to help avoid possible iatrogenic errors.