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    Acute Abdominal Pain with an Unusual Etiology: Splenic Infarction in a Diabetes Patient
    (Aves, 2016) Yalaza, Metin; Kafadar, Mehmet Tolga; Degirmencioglu, Gurkan; Turkan, Ahmet; Sen, Meral
    Splenic infarction is a rare clinical event caused by reduced blood flow to the spleen. Its presentation can mimic other causes of acute abdominal pain. The most frequent causes of splenic infarction include thromboembolic events, malignant hematologic neoplasms, and vasculitides. A few reports of single or multiple cases of diabetes-induced splenic infarction have been published in medical journals. Herein, we report a 67-year-old patient with diabetes-associated splenic infarction who presented to an emergency department with acute abdominal pain.
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    Acute Appendicitis in Pregnant Women: Our Clinical Experience
    (Canadian Soc Clinical Investigation, 2016) Turkan, Ahmet; Yalaza, Metin; Kafadar, Mehmet Tolga; Degirmencioglu, Gurkan
    Purpose: The purpose of this study was to analyse 13 patients who were treated in our clinic due to acute appendicitis during pregnancy. Methods: Records of the patients who received appendectomy with appendicitis diagnosis in our Turgut Ozal University Research and Application Hospital between January 2007 and December 2015 have been analyzed retrospectively. Results: Appendectomies were performed on 13 pregnant patients with an acute appendicitis diagnosis. Average age of the patients was 27.69 years (between 22-37 years). Most frequent complaint of the patients was abdominal pain and most frequent examination finding was tenderness at right lower quadrant. Ultrasonography was used in all cases for diagnosis. Surgery was decided with clinical diagnosis for five cases (38.5%) where appendix had not been identified with ultrasonography. While laparoscopic appendectomy was applied in one case (7.7%) and open appendectomy was applied using a McBurney incision in 12 cases (92.3%). Average hospitalization duration was 1.69 days. All patients were tracked together through the Gynaecology Department for two weeks after they had been discharged from the hospital. Preterm delivery, maternal and fetal loss did not occur. Conclusion: It is considered appropriate to apply ultrasonography routinely to all pregnant patients in whom acute appendicitis is suspected. Concern for maternal or fetal complication that may occur in consequence of an unnecessary surgery should not be at a level that will delay surgical treatment needed by the patient.
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    Docetaxel-induced Scleroderma in A Breast Cancer Patient: A Case Report
    (Aves, 2015) Kilic, Murat Ozgur; Yalaza, Metin; Bilgic, Celal Ismail; Dener, Cenap
    Paclitaxel and docetaxel are antineoplastic drugs derived from the yew tree, Taxus brevifolia. They are the members of the taxane family and act by inhibiting mitotic activity due to the suppression of microtubule depolymerization. They are used in the treatment of ovarian cancer, breast cancer, gastric cancer, small cell lung cancer, and head and neck cancer. In addition to side effects such as cardiotoxicity, neutropenia, arthralgia, and myalgia, they may also cause alopecia, urticaria, mucositis, acral erythema, pustular dermatitis, erythema multiforme, and scleroderma-like mucocutaneous lesions. Scleroderma is among the uncommon side effects of taxane antineoplastic agents. As was the case in few cases in literature, it usually begins with edematous changes in the proximal aspect of the extremities, and subsequently, sclerosis is developed in the skin. Scleroderma, which usually regresses with the discontinuation of the drug and with steroid therapy, may lead to severe contractions that require physical therapy and rehabilitation in some patients. In this paper, we presented a 60-year-old female patient in whom scleroderma developed because docetaxel chemotherapy for breast cancer because it is encountered rarely.
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    Isolated Jejunal Angiodysplasia: A Rare Cause of Massive Lower Gastrointestinal Bleeding Requiring Surgical Resection with an Unexpected Localization
    (Aves, 2016) Kafadar, Mehmet Tolga; Yalaza, Metin; Degirmencioglu, Gurkan; Inan, Aydin
    Angiodysplasias are most commonly observed in the cecum and ascending colon. The number of cases with angiodysplasias in the jejunum is very few. The endovascular transcatheter embolization method can be used in cases of lower gastrointestinal tract bleeding when endoscopy is not effective. According to the nature of lesion and source of bleeding, embolization is performed using the appropriate embolic agent. A surgical approach is used when endoscopic treatment methods and mesenteric angiography attempts fail. Here we present a rare case of jejunal anjiodysplasia with massive lower gastrointestinal bleeding treated with selective arterial embolization followed by urgent surgery because of a failed attempt to gain hemodynamic stability using both conservative and endoscopic methods.
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    Laparoscopic Nissen fundoplication with mesh-hiatoplasty: Single center experience and early-term results
    (Canadian Soc Clinical Investigation, 2016) Kafadar, Mehmet Tolga; Yalaza, Metin; Turkan, Ahmet; Surgit, Onder; Degirmencioglu, Gurkan; Nadir, Isilay
    Purpose: In this study we report early-term results of laparoscopic Nissen fundoplication with mesh hiatoplasty that we perform to treat gastroesophageal reflux disease. Methods: We retrospectively reviewed the medical records of 68 patients who underwent laparoscopic Nissen fundoplication with mesh hiatoplasty at our clinic. Thirty-six (53%) patients were male and 32 (47%) were female. The mean age of the study population was 46.1 (25-72) years. All patients underwent endoscopy, esophagus pH metry and manometry before the operation. All operations were performed under general anesthesia using five ports. In addition to Nissen fundoplication, all patients also underwent polypropylene mesh placement. Results: Preoperatively, all patients reported a burning sensation in the chest and regurgitation of the stomach contents up into the mouth. The mean time from symptom onset to operation was 28 (6-84) months. All patients were diagnosed with esophagitis in the preoperative endoscopic examination. The mean operative time was 80 (40-125) minutes, the median duration of hospital stay was 1.2 (1-4) days and the median follow- up time was 12 (2-30) months. Functional outcome was excellent in 65% of patients, good in 24.5%, moderately good in 7% and poor in 3.5%. Conclusion: Fundoplication with mesh hiatoplasty is a surgical procedure performed for the traetment of gastroesophageal reflux disease and hiatal hernia. Surgery can be safely carried out with low morbidity and mortality rates and constitutes an alternative to long-term drug therapy. We believe that this operation is beneficial since it reduces the rate of recurrences to a significant degree.
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    Male Breast Cancer
    (Aves, 2016) Yalaza, Metin; Inan, Aydin; Bozer, Mikdat
    Male breast cancer (MBC) is a rare disease, accounting for less than 1% of all breast cancer diagnoses worldwide. Although breast carcinomas share certain characteristics in both genders, there are notable differences. Most studies on men with breast cancer are very small. Thus, most data on male breast cancer are derived from studies on females. However, when a number of these small studies are grouped together, we can learn more from them. This review emphasizes the incidence, etiology, clinical features, diagnosis, treatment, pathology, survival, and prognostic factors related to MBC.