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Öğe Evaluation of postoperative residual curarization: a prospective clinical study(Malatya Turgut Özal Üniversitesi, 2024) Öterkuş, Mesut; Koca, Erdınc; Kutlusoy, SevgiBackground: Reversal of neuroblockade in general anesthesia is important to prevent possible complications. Currently, neostigmine and sugamedex are the agents of choice. The reversibility of blockade is evaluated by TOF (train-of-four ) as well as clinical observation. Our goal is to research and evaluate both agents in terms of complications and residual blockade. Materials and Methods: Our prospectively designed work included 100 cases operated under general anesthesia. demographic data, OF values, and complications were recorded. Results: A total of 100 patients, 63 neostigmine and 37 sugammedex, were consisted of in the search. The mean age of the sufferers was 41.9±16.9 years. When age was compared between the groups, it was found that the neostigmine (N) group was younger (p=0.027). There was a likeness between the groups in terms of surgical time, BMI (body mass index), Spo2, heart rate, mean arterial pressure, and total rocuronium consumption. The TOF value of the group N was 1(0.87-1), while that of the group sugamedex (S) was 1(0.91-1) and was found to be significant (p=0.045). There was no difference in TOF between cases who received an additional dose of rocuronium and those who did not receive an additional dose of rocuronium. Conclusions: As a result of the TOF values we obtained, we found that both agents were effective in removing the blockade, but the residual rate was statistically significantly lower in the sugamedex group, although not clinically significant. We did not encounter any complications in our study and we think that sugamedex is safer in terms of residual blockade.Öğe Morbidity and mortality results of COVID-19 variant in COVID-19 positive patients treated in the intensive care unit(Bayrakol Medical Publisher, 2023) Aydin, Ahmet; Koca, Erdinc; Kutlusoy, Sevgi; Kasapoglu, Umut SabriAim: COVID-19 has the potential to affect many systems and organs, resulting in serious clinical symptoms that necessitate admission to the intensive care unit. The purpose of this study was to examine the relationship between CAR, other laboratory findings, comorbidities, and mortality in patients infected with the original SARSCoV-2 or other variants.Materials and Methods: The data of 368 patients admitted to the intensive care unit with COVID-19 pneumonia between March 2020 and July 2021 were analyzed. These patients were divided into two groups. The first group included [(OC) Original SARSCoV-2 ] COVID-19 infected patients in the first period of the pandemic. The second group [(OV) Other Variants] included patients with COVID-19 infection due to other variants.Results: The mean age (Mean +/- SD) in the OC group was 69.79 +/- 11.77 years. The mean age of the patients in OC was higher than in the OV group (p=0.001). The most common comorbid disease in both groups was Hypertension (54.1%, 48.8%), followed by diabetes mellitus (DM) (30.2%, 31.6%). The mean age of the survivors in the OC and OV groups was lower (64.53 +/- 13.04, 57.85 +/- 16.78, p=0.001, p=0.001, respectively). It was observed that albumin and lymphocyte counts were lower in the deceased, while LDH, CRP, Neutrophil, procalcitonin, NLR and CAR were higher (p<0.05). Discussion: In critically ill COVID-19 patients, high CAR and NLR are good predictors of mortality. In the period when the variants were dominant, the mean age of the patients and the length of stay in the intensive care unit were lower.Öğe PROGNOSIS OF GERIATRIC COVID-19 PATIENTS ADMITTED TO INTENSIVE CARE UNIT ACCORDING TO VACCINATION STATUS(Turkish Geriatrics Soc, 2022) Aydin, Ahmet; Kacmaz, Osman; Koca, Erdinc; Kutlusoy, Sevgi; Kasapoglu, Umut Sabri; Oterkus, MesutIntroduction: As of June 27, 2022, the COVID-19 pandemic has caused over 540 million infections and 6.3 million deaths. We aimed to investigate the effect of the vaccine on the clinical course of elderly patients hospitalized in the intensive care unit and to determine the prognosis of the patients according to their vaccination status. Materials and Methods: The study included 157 patients over the age of 65. Patients were divided into two groups. The first group consisted of patients who were vaccinated with two doses of CoronaVac, and the second group consisted of patients who were not vaccinated. Demographic data of the patients, prehospital clinical frailty scales, Charlson Comorbidity Indexes, APACHE II scores, laboratory values, and patient prognoses were recorded. Results: Of the 157 patients, 93 (59.2%) were female, and the median age was 76 years (65-99). 96 (61.1%) patients were vaccinated and 61 (38.9%) patients were unvaccinated. Patients were grouped as survivors (n=26) and deceased. We found that APACHE II, prehospital clinical frailty scales, and Charlson Comorbidity Indexes scores were higher in patients who died. There was a significant difference between blood lymphocyte and ferritin levels and survival. The 28-day survival rate was higher and intensive care unit overall survival time were longer in the vaccinated group. Conclusions: We observed that the vaccinated patients had higher survival times and lower mortality rates than those who were not vaccinated. We think that it is important to vaccinate elderly patients and that additional doses may be needed.Öğe Yoğun bakım ünitesine kabul edilen hamile hastalarda COVID-19 ilişkili morbidite ve mortalite sonuçları(Malatya Turgut Özal Üniversitesi, 2024) Aydın, Ahmet; Kutlusoy, Sevgi; Koca, ErdıncAmaç: Çalışmamız, yoğun bakım ünitesine COVID-19 pnömonisi nedeniyle yatırılan gebe kadınların klinik özelliklerini ve anne-fetal sonuçlarını değerlendirmeyi amaçladı. Materyal ve Metot: Demografik veriler, başvuru şikayetleri, laboratuvar değerleri, gebelik sonuçları, doğum şekli ve yoğun bakım mortalitesi kaydedildi. Bulgular: 2 yıllık süreçte SARS-COV-2 enfeksiyonu nedeniyle hastanemizin yoğun bakım ünitesine toplam 10 hamile hasta yatırıldı. Yaşayan hastalarda yoğun bakım ünitesine girişte ölçülen arteriyel kan oksijen satürasyonu değerleri daha yüksekti. 10 hastadan 6'sı hayatını kaybetti. İnvazif mekanik ventilasyon gerektiren 7 hastadan sadece biri hayatta kaldı. Sonuç: Şiddetli semptomları olan COVID-19 ile enfekte hamile kadınlarda, uzamış yoğun bakım ünitesinde kalış süresi, artmış mortalite, yenidoğan ölümleri ve sezaryen gibi kötü obstetrik sonuçlar ve maternal morbiditelerin olduğunu tespit ettik.
