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    Mortality analysis of COVID-19 infection in chronic kidney disease, haemodialysis and renal transplant patients compared with patients without kidney disease: a nationwide analysis from Turkey
    (Pembegul, Irem, 2020) Savas Ozturk; Kenan Turgutalp; Mustafa Arici; Ali Riza Odabas; Mehmet Riza Altiparmak; Zeki Aydin; Egemen Cebeci; Taner Basturk; Zeki Soypacaci; Garip Sahin; Tuba Elif Ozler; Ekrem Kara; Hamad Dheir; Necmi Eren; Gultekin Suleymanlar; Mahmud Islam; Melike Betul Ogutmen; Erkan Sengul; Yavuz Ayar; Murside Esra Dolarslan; Serkan Bakirdogen; Seda Safak; Ozkan Gungor; Idris Sahin; Ilay Berke Mentese; Ozgur Merhametsiz; Ebru Gok Oguz; Dilek Gibyeli Genek; Nadir Alpay; Nimet Aktas; Murat Duranay; Selma Alagoz; Hulya Colak; Zelal Adibelli; Irem Pembegul; Ender Hur; Alper Azak; Dilek Guven Taymez; Erhan Tatar; Rumeyza Kazancioglu; Aysegul Oruc; Enver Yuksel; Engin Onan; Kultigin Turkmen; Nuri Baris Hasbal; Ali Gurel; Berna Yelken; Tuncay Sahutoglu; Mahmut Gok; Nurhan Seyahi; Mustafa Sevinc; Sultan Ozkurt; Savas Sipahi; Sibel Gokcay Bek; Feyza Bora; Bulent Demirelli; Ozgur Akin Oto; Orcun Altunoren; Serhan Zubeyde Tuglular; Mehmet Emin Demir; Mehmet Deniz Ayli; Bulent Huddam; Mehmet Tanrisev; Ilter Bozaci; Meltem Gursu; Betul Bakar; Bulent Tokgoz; Halil Zeki Tonbul; Alaattin Yildiz; Siren Sezer; Kenan Ates
    Background Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand as one of the established potential risk factors for severe coronavirus disease 2019 (COVID-19). Case morbidity and mortality rates for any type of infection have always been much higher in CKD, haemodialysis (HD) and RT patients than in the general population. A large study comparing COVID-19 outcome in moderate to advanced CKD (Stages 3–5), HD and RT patients with a control group of patients is still lacking. Methods We conducted a multicentre, retrospective, observational study, involving hospitalized adult patients with COVID-19 from 47 centres in Turkey. Patients with CKD Stages 3–5, chronic HD and RT were compared with patients who had COVID-19 but no kidney disease. Demographics, comorbidities, medications, laboratory tests, COVID-19 treatments and outcome [in-hospital mortality and combined in-hospital outcome mortality or admission to the intensive care unit (ICU)] were compared. Results A total of 1210 patients were included [median age, 61 (quartile 1–quartile 3 48–71) years, female 551 (45.5%)] composed of four groups: control (n = 450), HD (n = 390), RT (n = 81) and CKD (n = 289). The ICU admission rate was 266/1210 (22.0%). A total of 172/1210 (14.2%) patients died. The ICU admission and in-hospital mortality rates in the CKD group [114/289 (39.4%); 95% confidence interval (CI) 33.9–45.2; and 82/289 (28.4%); 95% CI 23.9–34.5)] were significantly higher than the other groups: HD = 99/390 (25.4%; 95% CI 21.3–29.9; P?
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    Pregnancy and its outcomes in hemodialysis patients in Turkey.
    (Pembegul, Irem, 2022) Hamad Dheir,; Özkan Güngör; Memnune Sena Ulu,; Ebru Gök Oğuz,; Necmi Eren,; Orçun Altunören,; Erhan Tatar,; Kadir Gökhan Atilgan,; Ibrahim Güney,; Eray Eroğlu,; Rüya Mutluay,; Ilter Bozaci,; Alper Alp,; Hakan Akdam,; Meltem Seziş Demirci,; Zeki Soypaçaci,; Özger Akarsu,; Saime Paydaş,; Zafer Ercan,; Ekrem Kara,; Cevat Topal,; Haldun Hakan Yavaş,; Nihan Tekkarişmaz,; Kenan Turgutalp; Can Hüzmeli,; Ayça Inci,; Güner Karaveli Gürsoy,; Ayşe Jini Güneş Keskin,; Bülent Huddam,; Ender Hür,; Abdulmecit Yildiz,; Garip Bekfilavioğlu,; Tuncay Şahutoğlu,; Mehmet Tuncay,; Simge Bardak,; Serkan Bakirdöğen,; Zülfükar Yilmaz,; Emrah Günay,; Onur Tunca,; Sinan Kazan,; Irem Pembegül Yiğit,; Hazen Saritaş,; Can Sevinç,; Hakan Kaptanoğullari,; Sibel Gökçay Bek,; Ilhan Kurultak,; Ali Değirmenci,; Murat Şakaci,; Ilhan Kiliç,; Zeki Aydin,; Hülya Çolak,; Erkan Dervişoğlu,; Garip Şahin,; Mehmet Deniz Ayli,; Savaş Sipahi,; Ülver Derici
    Background/aim: This study aimed to investigate pregnancy frequency and evaluate the factors affecting live births in hemodialysis (HD) patients. Materials and methods: Female HD patients whose pregnancy was retrospectively reported between January 1, 2014, and December 31, 2019. The duration of HD, primary disease, and the information on whether the pregnancy resulted in abortion, stillbirth, or live birth, whether the HD duration was prolonged after diagnosing the pregnancy and whether it accompanied preeclampsia were recorded. Results: In this study, we reached 9038 HD female patients’ data in the study. A total of 235 pregnancies were detected in 145 patients. The mean age was 35.42 (35 ± 7.4) years. The mean age at first gestation was 30.8 ± 6.5 years. The average birth week was 32 (28 –36) weeks. A total of 53.8% (no = 78) of the patients had live birth, 51.7% (no = 70) had at least one abortion in the first 20 weeks, and 13.1% (no = 19) had at least one stillbirth after 20 weeks. The rate of patients’ increased numbers of dialysis sessions during pregnancy was 71.7%. The abortion rate was 22.4% in those with increased HD sessions, whereas 79.3% in those not increased HD sessions (p < 0.001). Live birth frequency was 67.2% in the increased HD sessions group and 3.4% in those who did not differ in HD sessions (p < 0.001). Conclusion: For the first time, we reported pregnancy outcomes in HD female patients, covering all regions of Turkey. It has been observed that; increasing the number of HD sessions in dialysis patients will decrease fetal and maternal complications and increase live birth rates.