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Öğe Clitoral and labial sizes in women with PCOS(Taylor & Francis Inc, 2016) Kosus, A.; Kamalak, Z.; Kosus, N.; Hizli, D.; Eser, A.The aim of this study was to examine the external genital features in Turkish women with polycystic ovary syndrome (PCOS). Thirty-two newly diagnosed PCOS cases and 35 healthy women were included the study. All women underwent a thorough gynaecological examination. Clitoral length, and labia minora length and width were recorded. The groups were compared for features of external genital structures. Clitoral and labial lengths were significantly higher in PCOS group. There was a strong correlation between clitoral length and modified Ferriman-Gallwey score. The most effective predictor of PCOS was found to be clitoral length. Clitoral length alone predicted 99.9% of PCOS patients. There were some subclinical genital changes in women with PCOS. These changes in PCOS patients may be a sign of hyperandrogenism and might have diagnostic value in indistinct cases.Öğe Protective effect of curcumin on ovarian reserve in a rat ischemia model: an experimental study(I R O G Canada, Inc, 2017) Eser, A.; Hizli, D.; Namuslu, M.; Haltas, H.; Kosus, N.; Kosus, A.; Kafali, H.Purpose of investigation: To determine the protective effect of curcumin on ovarian reserve in a rat ischemia model. Materials and Methods: Thirty female Albino rats were randomly divided into two groups by time of unilateral, left ovary ischemia/reperfusion (group 1: two-hour ischemia / two-hour reperfusion; group 2: four-hour ischemia / four-hour reperfusion). Each group was subdivided into three subgroups, sham, control, and curcumin (intraperitoneal curcumin (200 mg/kg) simultaneously with reperfusion). Histological grading of ischemic indices of paraffin-embedded ovarian tissue using hematoxylin and eosin (H&E), and anti-Mullerian hormone (AMH) levels by enzyme-linked immunosorbent assay (ELISA), were measured 40 days later. Results: No difference was found between groups 1 and 2 or among subgroups within either group for right and left ovary grades. AMH levels were significantly higher in the curcumin subgroup compared to sham and control within group 2 and in group 2 versus group 1 curcumin subgroups. Conclusion: Curcumin maintains and protects ovarian functions in an ischemia-reperfusion rat model.Öğe The circulating betatrophin and irisin levels in polycystic ovary syndrome patients with and without insulin resistance(Wiley-Blackwell, 2016) Bal, A.; Cihanbeyoglu, S.; Kazanci, F. Hacievliyagil; Kilic, N.; Yilmaz, Y. Yaral; Celik, H. T.; Eser, A.[Abstract Not Available]
