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    Investigation of the prevalence of COPD in the relatives of COPD patients aged 35 and over
    (Malatya Turgut Özal Üniversitesi, 2022) Türkkan, Sinan; Geçkil, Ayşegül Altıntop; Karadağ, Müge; Ermiş, Hilal
    Background: The aim of this study was to investigate the prevalence of of Chronic Obstructive Pulmonary Disease (COPD) in the relatives (siblings, parents, children) of the patients followed up with the diagnosis COPD. Material and Method: 78 patients diagnosed with COPD based on anamnesis, physical examination, pulmonary function test (PFT) and X-ray findings and 139 relatives aged 35 and over were included in the study. Sociodemographic records of the patients and their relatives were obtained. PFT was performed on the relatives of the patients, and the alpha-1 antitrypsin enzyme (AAT) level was measured. Results: FEV1/FVC<0,7 was found in 24 (18,6%) of the relatives of the patients included in the study, whose PFT could be performed. The relatives of the patients with FEV1/FVC<0,7 were women 24/7 (29,2%) and 90% had a smoking history. Most of our COPD patients and their relatives had a history of biomass exposure and smoking. AAT enzyme levels of all patient relatives were within normal limits (1,23±0,64 gr/L). In the results of study; the prevalence of COPD detected by PFT among the relatives of patients aged 35 and over was 18,6%. The prevalence of COPD was found to be 25.4% in the subgroup analysis of patients' relatives aged 40 years and over and those with a smoking history. Conclusion: As a result of the study, it was shown that the first degree relatives of a COPD patient could develop COPD at a rate of 25.4% after the age of 40. For this reason, every patient and patient relatives who come to the examination should be informed about the disease and risk factors, and their smoking status should be evaluated.