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    Evaluation of Pulmonary Function Tests in Working Firemen
    (Aves, 2014) Demir, Sema; Oztuna, Derya
    Objective: During interventions, firemen are exposed to fire smoke. Fire smoke contains many air pollutants. Smoke exposure may increase the risk of pulmonary and cardiovascular diseases. The aim of this study was to evaluate the effect of long-term occupational smoke inhalation on respiratory functions and related risk factors in working firemen. Methods: Between February and March 2012, 523 working firemen were retrospectively evaluated within the scope of a screening program in Ankara Numune Training and Research Hospital. The study included 250 firemen actively participating in a fire and a control group of 273 firemen working in the office. Detailed evaluation of the firemen included age, gender, height, weight, spirometric measurements (FEV 1, FVC, FEV1 / FVC, PEF, FEF25-75), smoking status and duration, duration of work, and comorbidities. Results: According to the results obtained from the study, FEV1 values were significantly decreased in firemen actively participating in firefights compared to the low-risk group. The duration of the study did not significantly affect pulmonary functions. Conclusion: Respiratory functions decrease in active working firefighters. Development of diseases related to exposure to smoke may be prevented by the development of more effective apparatus protecting from smoke, working in cycles in different fire types, quitting smoking, and regular annual screenings.
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    Oxygen Desaturation and Beck Depression Inventory Relationship in Patients with Obstructive Sleep Apnea Syndrome
    (Galenos Publ House, 2016) Demir, Sema
    Objective: Sleep fragmentation occurs proportionally with the severity of disease in Obstructive sleep apnea syndrome (OSAS) patients. Deep sleep decreases in patients. Depression incidence increases depending on poor sleep, cognitive impairment, and the character and personality changes. Our aim in this study, we examined the relationship between oxygen desaturation and the Beck depression index (BDI) in patients with OSAS. Materials and Methods: Two hundred nineteen patients with polysomnography (PSG) and BDI records were included in this cross-sectional and retrospective study. The age range of patients was in 1878. In OSAS group, 57 patients were mild [respiratory disturbance index (RDI): 5-15)]; 54 patients were moderate (RDI: 15.1-30); 52 patients were severe (RDI: > 30). Fifty-six patients (RDI < 5) were control group. Exclusion criterions were major depression, other psychiatric disorders and to receive depression treatment when PSG recordings were made. The results of Beck depression inventory were evaluated according to the criterion that BDI: 0-13 normal; BDI: 14-19 mild depression, BDI: 20-28 moderate depression, BDI: > 29 severe depression. Results: The results of Beck Depression Index were observed as normal or mild depression at whole study population. The oxygen desaturation in patients with OSAS was increasing due to the severity of disease. But, between BDI and the oxygen desaturation there was no correlation in OSAS patients as compared with the control group. Conclusion: Depression is common due to chronic insomnia and especially fragmentation of sleep in OSAS. However, in our study, we observed the patients with normal or mild depressive symptoms. Between BDI and the oxygen desaturation there was no correlation. Hypoxemia was not provoked depression, however was suggested in the mood changes that due to insufficient sleep and the reduction of sleep depth.
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    Redcell Distribution Width, Mean Platelet Volume, Platelet Distribution Width Parameters and Disease Severity Relationship in Patients with Obstructive Sleep Apnea Syndrome
    (Galenos Publ House, 2016) Demir, Sema
    Objective: To evaluate the relationship between redcell distrubution width (RDW), platelet distribution width (PDW), mean platelet volume (MPV) parameters and the disease severity in Obstructive sleep apnea syndrome (OSAS) patients; to benefit from the biomarkers to take early measures on disease treatment, follow-up and complications (as thromboembolic events and cardiovascular diseases). Materials and Methods: Our study is a retrospective and a cross-sectional study and we planned to asses polysomnography (PSG) records of the patients. Patients who were diagnosed with OSAS by PSG were grouped as 108 mild patients with [Respiratory Disturbance Index (RDI): 5-14.9]; 69 moderate patients (RDI: 15-30); 66 severe patients (RDI>30) and 117 patients were control group (RDI<5). The age range was between 18 and 78. Inclusion criterions were routine blood count, RDW, MPV and PDW. Results: Three hundred and sixty patients were enrolled in the study. 74.2% of them were male; mean age was 46.5. The average patient O-2 saturation was 93.2. When moderate OSAS group was compared with the control group, hematocrit (Htc) (p=0.004) and hemoglobin (Hb) (p=0.002) were found to be significantly increased. When severe OSAS group was compared with the control group, MPV (p=0.017) was decreased significantly, Htc (p=0.006) and Hb (p=0.02) were found to be significantly increased. Conclusion: In our study, when the other groups and the control group were compared, we observed significantly increased Hb and Htc values in moderate and severe OSAS groups, however some other studies gives an increase in MPV we observed a decrease in severe group. Having few number of patients in moderate and severe OSAS groups may have led to such results. Therefore, more extensive and prospective studies are needed.