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Öğe Autonomic Cardiac Activity in Patients with Smoking and Alcohol Addiction by Heart Rate Variability Analysis(Canadian Soc Clinical Investigation, 2016) Yuksel, Ramazan; Yuksel, Rabia Nazik; Sengezer, Tijen; Dane, SenolPurpose: Smoking and alcohol addictions are common and worldwide. In the present study, we aimed to investigate the effects of these addictions on cardiac rhythm using heart rate variability (HRV) analysis. Methods: Addicts (n=42 men: 22 cigarette; 20 cigarette and alcohol) and age-matched controls (n=34 men) were included in the study. All patients fulfill the criteria for dependence according to DSM-IV-TR. Electrocardiography (ECG) recordings were obtained for a total of 30 minutes. Fagerstrom Nicotine Addiction Test (FNAT) and CAGE questionnaire (Cut down, Annoy, Guilt, Eye opener) was applied to all patients. Results: Almost all HRV parameters were significantly decreased in cigarette and cigarette and alcohol addicts compared with controls (p<0.05). The mean heart rate (bpm) increased in both addict groups compared with control group, and this increase was particularly significant in cigarette and alcohol addicts. Conclusions: The cardiac autonomic balance shifted in favor of sympathetic activity by suppressing the parasympathetic activity in addicts; therefore, the present study shows that smoking and/or alcohol addiction leads to sympathetic activation and parasympathetic inhibition. Reduced vagal activity also predisposes to cardiac arrhythmias. This suggests an increased risk of cardiovascular mortality in subjects with smoking and alcohol addiction.Öğe Effects of Long-Term Training Program on Static and Dynamic Balance in Young Subjects(Canadian Soc Clinical Investigation, 2016) Gurkan, Alper Cenk; Demirel, Havva; Demir, Merve; Atmaca, Emine Seyda; Bozoyuk, Gulnihal; Dane, SenolPurpose: The purpose of this study was to examine the efficacy of a long-term training program of 10 weeks on static and dynamic balance parameters in a young healthy population. Methods: Participants were 35 young healthy female subjects. Balance measurements were done using the Flamingo Balance Test (FBT) for static balance and the Star Excursion Balance Test (SEBT) for dynamic balance. Results: Dynamic balance points increased and static balance points decreased after a 10 week training protocol compared with before training, indicating improvement in both dynamic and static balance. Conclusions: These results indicate that long term training resulted in an improvement both static and dynamic balance. Training can be suggested for patients with balance problems.Öğe Effects of neurofeedback therapy in healthy young subjects(Canadian Soc Clinical Investigation, 2016) Altan, Sumeyra; Berberoglu, Bercim; Canan, Sinan; Dane, SenolPurpose: Neurofeedback refers to a form of operant conditioning of electrical brain activity, in which desirable brain activity is rewarded and undesirable brain activity is inhibited. The research team aimed to examine the efficacy of neurofeedback therapy on electroencephalogram (EEG) for heart rate, electrocardiogram (ECG) and galvanic skin resistance (GSR) parameters in a healthy young male population. Methods: Forty healthy young male subjects aged between 18 to 30 years participated in this study. Neurofeedback application of one session was made with bipolar electrodes placed on T-3 and T-4 (temporal 3 and 4) regions and with reference electrode placed on PF1 (prefrontal 1). Electroencephalogram (EEG), electrocardiogram (ECG) and galvanic skin resistance (GSR) were assessed during Othmer neurofeedback application of one session to regulate slow wave activity for forty minutes thorough the session. Data assessed before neurofeedback application for 5 minutes and during neurofeedback application of 30 minutes and after neurofeedback application for 5 minutes throughout the session of 40 minutes. Means for each 5 minutes, that is to say, a total 8 data points for each subjects over 40 minutes, were assessed. Results: Galvanic skin resistance increased and heart rate decreased after neurofeedback therapy. Beta activity in EEG increased and alfa activity decreased after neurofeedback therapy. Conclusions: These results suggest that neurofeedback can be used to restore sympathovagal imbalances. Also, it may be accepted as a preventive therapy for psychological and neurological problems.Öğe HEART RATE VARIABILITY DIFFERS BETWEEN RIGHT- AND LEFT-HANDED INDIVIDUALS(Ammons Scientific, Ltd, 2014) Yuksel, Ramazan; Arslan, Muzeyyen; Dane, SenolPrevious studies reported reduced longevity in left-handers with the suggestion that it may be associated with different heart diseases. Therefore, differences in heart rate variability (HRV), an index of autonomic cardiac activity, were examined for right-and left-handed individuals. 120 healthy young university students (75 women, 45 men; M age = 20.4 yr., SD = 1.5) volunteered. Handedness was assessed with the Edinburgh Handedness Inventory and HRV was measured via electrocardiography. The results suggest that the left-handers' HRV was significantly different from that of right-handers on several parameters. The atypical cerebral organization of left-handers may be related to an imbalanced autonomic system that results in higher frequencies of heart irregularities.Öğe Is it possible to remove heavy metals from the body by wet cupping therapy (Al-hijamah)?(Natl Inst Science Communication-Niscair, 2016) Gok, Sumeyye; Kazanci, Fatmanur Hacievliyagil; Erdamar, Husamettin; Gokgoz, Nurcan; Hartiningsih, SitiSugih; Dane, SenolWet cupping therapy (WCT) is a traditional blood-letting method recommended for treating a lot of diseases. Al-hijamah is WCT of prophetic medicine that's also called the triple S technique that includes skin suction, scarification and second suction. Its mechanism of action is still unknown but it is believed to remove toxic substances from the body according to the evidence-based Taibah mechanism (Taibah theory). In this study, the aim was to compare wet cupping blood and venous blood samples in terms of heavy metals concentrations. 24 healthy volunteers were enrolled in this study. After venous blood samples were drawn, WCT (Al-hijamah) was performed and wet cupping blood samples were taken. In order to measure the levels of heavy metals all samples were analyzed by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In the present study, all levels of selected heavy metals were significantly higher in wet cupping blood than venous blood. It may be possible to remove heavy metals from the body through wet cupping therapy.Öğe Laterality Does Not Affect the Depth Perception, but Interpupillary Distance(Hindawi Ltd, 2013) Aslankurt, Murat; Aslan, Lokman; Aksoy, Adnan; Ozdemir, Murat; Dane, SenolIn this study, which investigates the relationship between the levels of stereopsis with eye and hand dominance or interpupillary distance, 120 healthy young volunteers were investigated. Eye dominance was determined by modified Miles technique following a complete eye examination. Handedness was assessed with the Edinburgh handedness inventory. Interpupillary distance was measured with millimetric ruler. Stereoacuity was measured in both contour (Titmus test) and random dot (TNO test) stereograms. The stereopsis scores were evaluated in terms of hand or eye dominance. The correlation between stereopsis score and interpupillary distance was assessed. Main outcome measures were stereopsis scores according to hand and eye dominance. As a result, right-and left-handed individuals showed no differences in terms of stereopsis. No differences were found in stereopsis scores between right- and left-eye dominant people. There was a correlation between interpupillary distance and the depth of stereopsis (r = -0.248, P < 0.05). Contrary to the expectation, the left and right dominant individuals did not differ in levels of stereopsis. Interpupillary distance has a positive effect on stereopsis.Öğe Left-right asymmetry in neck lymph nodes distribution in patients with bilateral laryngeal cancer(Springer France, 2014) Yoruk, Ozgur; Yuksel, Ramazan; Yuksel, Yasemin; Dane, SenolWe aimed to examine left-right asymmetry in involved and total neck lymph nodes distribution in patients with bilateral laryngeal cancer in the present study. Forty-six patients with bilateral laryngeal cancer was included the study. The oncologic database of our otorhinolaryngology department was used. The right and left lymph node with and without involvement by cancer cells counts were retrieved from pathological reports. The numbers of both involved and total neck lymph nodes were significantly higher on right side than on left side for all neck levels in laryngeal malignancies. The results of the present study suggest the existence of a left-right asymmetry in neck lymph node distribution and in the neck lymph node distribution involved by laryngeal cancer cells. The stronger cell-mediated immune activity in the left side of humans may be associated with the blocking of the metastatic invasion of cancer cells from laryngeal malignancies in the left body side.Öğe Moving Dry Cupping Therapy Reduces Upper Shoulder and Neck Pain in Office Workers(Canadian Soc Clinical Investigation, 2015) Arslan, Muzeyyen; Yaman, Gulnur; Ilhan, Esra; Alemdag, Murat; Bahar, Arzu; Dane, SenolPurpose: The effectiveness of active dry cupping of the upper shoulder and neck to alleviate pain caused by office workers will be investigated. Methods: This randomized, parallel-group trial compared the effectiveness and safety of dry moving cupping therapy for office workers whose neck pain had persisted at least 5 weeks. Those randomized to cupping received up to 10 dry moving cupping therapy sessions over a 5 week period. The study was completed with 40 healthy women subjects who worked at one univeristy in Turkey, with 20 as control and 20 as the study group. Results: Participants mean score of pain on neck was 5.55 (SD:0.57) for pre-test and 2.7 (SD:0.27) for post-test. The decrease of score of pain between pre- and post-test was statistically significant (t=10.14, p=0.002). In the control group there was no significant change in pain score in the statistical significant (t=0.326, p=0.748). Conclusions: Cupping therapy is a non-invasive and harmless therapeutic application and it can be confidently used to reduce the upper shoulder and neck pain in office. It should be considered for all musculoskeletal pain conditions as a complementto medical treatment.Öğe Reflexological Therapy Induces a State of Balance in Autonomic Nervous System(Canadian Soc Clinical Investigation, 2015) Isik, Bunyamin; Aydin, Duygu; Arslan, Muzeyyen; Dane, SenolPurpose: Reflexology activate all body systems physically, mentally and emotionally by relieving pain and relaxing the body, in a manner similar to acupuncture and cupping therapies. The aim of this study was to examine the effect of reflexological therapy on heart rate variability (HRV) parameters in a healthy population. Methods: Participants were twenty-six healthy subjects (8 women, 18 men, median age=32.77 years, SD=8.04). All reflexology procedures were applied by a reflexology practitioner. The reflexology practitioner used thumbs and fingers to apply appropriate pressure to reflexology points, especially the heart point in both feet. The recording ECG was applied 1 hour before and 1 hour after reflexological therapy. Subjects rested for 10 minutes without recording ECG in order to stabilize autonomic parameters. The digital signals were then transferred to a laptop and analyzed using LabChart (R) software (MLS310/7 HRV Module). Results: Almost all HRV parameters increased and heart (pulse) rate and LF/HF ratio decreased after reflexological therapy compared with before reflexological therapy in healthy persons. Conclusions: These results indicate for the first time in humans that reflexology might induce a state of balance between sympathetic and parasympathetic systems and might be helpful to prevent possible cardiac arrhythmias. Therefore, reflexology may be accepted as a complementary therapy method for many cardiac problems, especially tachycardia and other cardiac arrhythmias.Öğe Right-sided lateralization of skin temperature in healthy young persons(Canadian Soc Clinical Investigation, 2016) Demirel, Havva; Bahar, Arzu; Gokgoz, Nurcan; Arslan, Muzeyyen; Dane, SenolPurpose: Previous studies reported a peripheral immune asymmetry and lateralization of different paired organ cancers. Because of the close relationship of immune system with body temperature, the aim of the study was to test the possible lateralization of skin temperature. Materials and Methods: Four hundred sixty three healthy subjects (325 women, 138 men) with an average age of 23.62 years (SD = 8.65) participated in this study. All skin temperature measurements were done 8:00-9:00 a.m. Skin temperature was assessed for three different points in skin: axillary, thumb and external auditory. Results: Skin temperature was statistically significantly higher on the right side of the body than on the left side, when measured by axillary and thumb temperatures. But there was no statistically significant difference in external auditory temperature. Conclusion: The asymmetry of skin temperature may result from the peripheral immune asymmetry or the asymmetric lymph node distribution.Öğe The effect of sleep deprivation on heart rate variability in shift and non-shift physicians(Canadian Soc Clinical Investigation, 2015) Cebeci, Sevsen; Canbal, Metin; Yuksel, Ramazan; Cetin, Medine; Caliskan, Yasemin; Dane, SenolPurpose: Higher LF/HF ratio and lower heart rate variability have been reported among shift compared with non-shift workers. We aimed to investigate the possible harmful effects of sleep deprivation on cardiac rhythm, specifically heart rate variability (HRV), in work shift physicians. Patients and Methods: Eighty seven healthy male physicians participated in this study. The present study was done in Ankara, Turkey, from January to September 2014. Work shift (sleep deprivation) group (n=45) remained awake for 26 h. Non-work shift group slept in their homes. ECG (HRV) was applied at 9 am for both shift and non-shift groups. Results: Almost all HRV parameters, except LF/HF, decreased in the work shift group compared with the non-shift group. Conclusions: Sleep deprivation due to work shift may cause sympathovagal imbalances by affecting the biological rhythm.Öğe The effect of traditional wet cupping on shoulder pain and neck pain: A pilot study(Elsevier Sci Ltd, 2016) Arslan, Muzeyyen; Gokgoz, Nurcan; Dane, SenolObjectives: Wet cupping therapy (WCT) is a traditional complementary method recommended to decrease the symptoms of a lot of diseases and used in the treatment of pain syndromes. In this pilot study, the possible effects of wet cupping therapy on nonspecific neck and upper shoulder pain were investigated. Methods: Sixty one eligible volunteer participants with nonspecific neck and upper shoulder pain for at least 3 months were allocated. The Numeric Rating Scale (NRS) was used to assess pain scores. Pain scores were recorded before and after wet cupping therapy. Results: The mean scores of neck pain in study group were 7.02 (SD = 1.8) before and 3.70 (SD = 2.2) after cupping therapy. The decrease of pain scores between pre- and post-test was statistically significant (p < 0.05). Discussion: It can be stated that WCT has potential therapeutic effect in nonspecific neck and upper shoulder pain. Future full-scale randomized controlled trials will be needed to provide firm evidence of the effectiveness of this intervention. (C) 2016 Elsevier Ltd. All rights reserved.Öğe The Potential Beneficial Effects Of Hand And Foot Bathing On Vital Signs In Women With Caesarean Section(Canadian Soc Clinical Investigation, 2016) Cal, Elif; Cakiroglu, Busra; Kurt, Ayse Nur; Hartiningsih, Siti Sugih; Suryani; Dane, SenolPurpose: Hand-foot bathing therapy is a simple technique to induce sensations of comfort and relaxation. The aim of this study was to examine the effect of hand and foot bathing therapy on vital signs in women following caesarean section. Methods: Participants were sixty women with caesarean section. They divided to two groups: (1) study group (n= 30, median age= 26.67 years, SD= 2.04); and, (2) control group (n= 30, median age= 27.75 years, SD= 1.09). Vital signs were measured for 5 minutes before and for 30 minutes after the hand and foot bathing therapy. Results: Pain score, systolic and diastolic blood pressures and heart and breath rates decreased after hand and foot bathing therapy. Differences between before and after therapy were statistically significantly. Conclusions: These results indicate that hand and foot bathing therapy might be helpful to restore the vital signs in post-operative patients by decreasing anxiety and psychological stress.Öğe The role of reactive oxygen species and oxidative stress in carbon monoxide toxicity: An in-depth analysis(Maney Publishing, 2014) Akyol, Sumeyya; Erdogan, Serpil; Idiz, Nuri; Celik, Safa; Kaya, Mehmet; Ucar, Fatma; Dane, SenolThe underlying mechanism of the central nervous system (CNS) injury after acute carbon monoxide (CO) poisoning is interlaced with multiple factors including apoptosis, abnormal inflammatory responses, hypoxia, and ischemia/reperfusion-like problems. One of the current hypotheses with regard to the molecular mechanism of CO poisoning is the oxidative injury induced by reactive oxygen species, free radicals, and neuronal nitric oxide. Up to now, the relevant mechanism of this injury remains poorly understood. The weakening of antioxidant systems and the increase of lipid peroxidation in the CNS have been implicated, however. Accordingly, in this review, we will highlight the relationship between oxidative stress and CO poisoning from the perspective of forensic toxicology and molecular toxicology.Öğe Wet Cupping (Hijamah) Increases Sleep Quality(Canadian Soc Clinical Investigation, 2015) Cikar, Selma; Ustundag, Gamze; Haciabdullahoglu, Seda; Yuksel, Sevda; Dane, SenolPurpose: Wet cupping (hijamah) therapy relieves the pain and relaxes the body. The research team aimed to examine the efficacy of wet cupping therapy on the sleep quality parameters in a healthy population. Methods: Participants were seventy-five healthy subjects (50 women, 25 men, median age = 29.61 years, SD = 8.92). Wet cupping was applied by a cupping practitioner. The assessment of the sleep quality parameters by Pittsburg Sleep Quality Index Inventory was applied one hour before and one month after wet cupping therapy. Results: All sleep quality parameters were positively affected after wet cupping therapy in healthy subjects. Conclusions: Wet cupping therapy should be considered as a complementary therapy method for people with sleep problems.Öğe Wet Cupping Therapy Restores Sympathovagal Imbalances in Cardiac Rhythm(Mary Ann Liebert, Inc, 2014) Arslan, Muzeyyen; Yesilcam, Nesibe; Aydin, Duygu; Yuksel, Ramazan; Dane, SenolObjectives: A recent study showed that cupping had therapeutic effects in rats with myocardial infarction and cardiac arrhythmias. The current studyaimed to investigate the possible useful effects of cupping therapy on cardiac rhythm in terms of heart rate variability (HRV). Materials and methods: Forty healthy participants were included. Classic wet cupping therapy was applied on five points of the back. Recording electrocardiography (to determine HRV) was applied 1 hour before and 1 hour after cupping therapy. Results: All HRV parameters increased after cupping therapy compared with before cupping therapy in healthy persons. Conclusions: These results indicate for the first time in humans that cupping might be cardioprotective. In this study, cupping therapy restored sympathovagal imbalances by stimulating the peripheral nervous system.












