Investigation of the Effectiveness of Polyurethane Composites Containing Gelatin at Different Rates on the Release of Ciprofloxacin
Künye
Açari, I. K. (2021). Investigation of the Effectiveness of Polyurethane Composites Containing Gelatin at Different Rates on the Release of Ciprofloxacin. Journal of the Chemical Society of Pakistan, 43(6).Özet
Recently, polyurethane materials are widely used for many application areas such as drug
delivery systems, biomaterial production, etc. In this study, polyurethane structures containing
different amounts of gelatin (5%, 10%) were prepared. A release system was designed with
ciprofloxacin adsorption to the prepared polyurethane structures. The structural characterization,
thermal properties, surface morphologies of the designed system were determined using appropriate
techniques. Monitoring of ciprofloxacin release was carried out by UV-spectrophotometer. It was
determined that polyurethane structures containing different proportions of gelatin supported the
adsorption of ciprofloxacin and the release slowed down with the increasing gelatin ratio. With this
study, many drug delivery systems that can release at different rates and durations depending on the
amount of gelatin additive can be designed.