Kurum Yazarı "Akbulut, Ekrem" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
-
The Effects of SARS CoV-2 nsp13 Mutations on the Structure and Stability of Helicase in Chinese Isolates
Akbulut, Ekrem (İstanbul Üniversitesi / İstanbul University, 2022)Objective: Coronavirus Disease 2019 (COVID19) is a viral disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2). The high mutation propensity of the SARS CoV-2 genome is one of the biggest threats ... -
Investigation of changes in protein stability and substrate affinity of 3CL-protease of SARS-CoV-2 caused by mutations
Akbulut, Ekrem (Sociedade Brasileira de Genetica, 2022)3CLpro of SARS-CoV-2 is one of the enzymes required for the replication process of the virus responsible for the COVID-19 pandemic. In this study, changes in protein stability and substrate affinity caused by mutations ... -
Mutations in the SARS CoV-2 spike protein may cause functional changes in the protein quaternary structure
Akbulut, Ekrem (Turkish Journal of Biochemistry, 2021)Objectives: This study aimed to model the changes resulting from mutations in surface (spike/S) glycoproteins, which play a key role in the entry of the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) into ... -
SARS CoV-2 Spike glycoprotein mutations and changes in protein structure
Akbulut, Ekrem (Trakya Üniversitesi, 2021)Severe Acute Respiratory Syndrome Corona Virus-2 (SARS CoV-2) is a single-stranded positive polarity RNA virus with a high virulence effect. Spike (S) glycoprotein is the outermost component of the SARS CoV-2 virion and ...