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SARS CoV-2 Spike glycoprotein mutations and changes in protein structure
(Trakya Üniversitesi, 2021)
Severe Acute Respiratory Syndrome Corona Virus-2 (SARS CoV-2) is a single-stranded positive polarity RNA virus with a high virulence effect. Spike (S) glycoprotein is the outermost component of the SARS CoV-2 virion and ...
Mutations in the SARS CoV-2 spike protein may cause functional changes in the protein quaternary structure
(Turkish Journal of Biochemistry, 2021)
Objectives: This study aimed to model the changes resulting from mutations in surface (spike/S) glycoproteins, which play a key role in the entry of the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) into ...
The role of A268V exon-7 polymorphism of PPARA in development of axial spondyloarthritis
(WALTER DE GRUYTER GMBHGENTHINER STRASSE 13, D-10785 BERLIN, GERMANY, 2021)
Objectives: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that mainly affects the axial skeleton. Peroxisome proliferator activated receptor alpha (PPARA) is an intracellular transcription factor, which ...