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Cloning and Expression vgb-kfo Genes in E. coli and Microbial Chondroitin Sulfate Production
Erenler, Ayşe Şebnem; Geçkil, Hikmet; Akpolat, Nusret; Sevimli, Reşit; Ülke, Esra; Aliyeva, Aygün (AMER SCIENTIFIC PUBLISHERS, 2019)This study focused on a new plasmid and new recombinant strain developed for the production of microbial chondroitin sulfate a new and limited area of study the strategies we applied for the production of microbial chondroitin ... -
Microbial chondroitin sulfate in experimental knee osteoarthritis model investigation of chondroprotective effect
Sevimli, Reşit; Erenler, Ayşe Şebnem; Bay Karabulut, Aysun; Akpolat, Nusret; Geçkil, Hikmet (Verduci Editore, 2021)OBJECTIVE: Chondroitin sulfate (CS) is a glycosaminoglycan with proven anti-inflammatory, anti-apoptotic, anti-oxidant properties. CS increases type II collagen and proteoglycan synthesis in human joint chondrocytes. CS ...