Yazar "Akbulut, Ekrem" için listeleme
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Effects of Salicylic Acid on Fatty Acid Gene Expression in Carthamus tinctorious L. cv. Dinçer under Pendimethalin Stress
Akbulut, Ekrem (Munzur Üniversitesi, 2020)Pendimethalin is a member of the dinitroaniline class herbicide. It used to control most annual grasses and many annual broad-leaved weeds. Salicylic acid acts as an endogenous signal molecule in charge of inducing ... -
The Effects of SARS CoV-2 nsp13 Mutations on the Structure and Stability of Helicase in Chinese Isolates
Akbulut, Ekrem (İstanbul Üniversitesi / İstanbul University, 2022)Objective: Coronavirus Disease 2019 (COVID19) is a viral disease caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2). The high mutation propensity of the SARS CoV-2 genome is one of the biggest threats ... -
Endoplasmic reticulum aminopeptidase-1 polymorphism increases the risk of rheumatoid arthritis
Akbulut, Ekrem; Yıldırım, Tülay; Öztürk, Onur (2022)Objectives: Endoplasmic reticulum aminopeptidase-1 (ERAP1) polymorphic changes cause autoimmunity. To understand the contribution of ERAP1 to the occurrence of rheumatoid arthritis (RA) disease, we investigated ... -
Investigation of changes in protein stability and substrate affinity of 3CL-protease of SARS-CoV-2 caused by mutations
Akbulut, Ekrem (Sociedade Brasileira de Genetica, 2022)3CLpro of SARS-CoV-2 is one of the enzymes required for the replication process of the virus responsible for the COVID-19 pandemic. In this study, changes in protein stability and substrate affinity caused by mutations ... -
Mutations in Main Protease of SARS CoV-2 Decreased Boceprevir Affinity
Akbulut, Ekrem (INST TECNOLOGIA PARANA, 2022)The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health emergency. The main protease (Mpro) is crucial for the life cycle of coronaviruses. ... -
Mutations in the SARS CoV-2 spike protein may cause functional changes in the protein quaternary structure
Akbulut, Ekrem (Turkish Journal of Biochemistry, 2021)Objectives: This study aimed to model the changes resulting from mutations in surface (spike/S) glycoproteins, which play a key role in the entry of the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) into ... -
Pendimethalin ve Salisilik Asit Uygulamalarının Carthamus tinctorius L. cv. “Remzibey” Yağ Asidi Desatüraz Genlerinin Anlatımı Üzerine Etkisi
Akbulut, Ekrem (Iğdır Üniversitesi, 2020)Aspir (Carthamus tinctorius L.), tohumlarında yüksek kaliteye sahip doymamış yağ asitlerinden oleikasit ve α-linolenik asit içeren endüstriyel hammadde kaynağı olma özelliğine sahip önemli bir yağ bitkisidir.Pendimethalin ... -
The role of A268V exon-7 polymorphism of PPARA in development of axial spondyloarthritis
Akbulut, Ekrem; Yolbas, S; Ozgen, M (WALTER DE GRUYTER GMBHGENTHINER STRASSE 13, D-10785 BERLIN, GERMANY, 2021)Objectives: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that mainly affects the axial skeleton. Peroxisome proliferator activated receptor alpha (PPARA) is an intracellular transcription factor, which ... -
SARS CoV-2 nsp1 Mutasyonlarının Protein Yapıda Ortaya Çıkardığı Değişimler
Akbulut, Ekrem (Munzur Üniversitesi, 2020)Şiddetli akut solunum yolu sendromu koronavirüsü 2 (SARS CoV-2) pozitif polariteli ve tek iplikli bir RNA virüsüdür. Virüsün sebep olduğu COVID19 hastalığı on ay gibi kısa bir sürede 900 binden fazla insanın ölümüne neden ... -
SARS CoV-2 Spike glycoprotein mutations and changes in protein structure
Akbulut, Ekrem (Trakya Üniversitesi, 2021)Severe Acute Respiratory Syndrome Corona Virus-2 (SARS CoV-2) is a single-stranded positive polarity RNA virus with a high virulence effect. Spike (S) glycoprotein is the outermost component of the SARS CoV-2 virion and ...